As of April 2025, all RiMUPs for evaluation by the Pharmacovigilance Section, Centre of Compliance & Quality Control (PKKK) [previously requiring manual submission] should be submitted through the QUEST 3+ system.

Important Note: RiMUP submissions for evaluation by the Pharmacovigilance Section should be submitted as a single variation only (bundling with other variation types is NOT accepted, as the evaluation will be conducted by different officers).

Please ensure all other variations are submitted and approved, BEFORE submitting the RiMUP for evaluation by the Pharmacovigilance Section (i.e., no bundling).

For further details, please refer to our previous announcement and the updated guidelines.